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Home > News & events > Publications

Publications

Nature 456, 107-111 (6 November 2008) | doi:10.1038/nature07343

Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases
Pilar Redondo, Jesus Prieto, Ines G. Munoz, Andreu Alibes, Francois Stricher, Luis Serrano, Jean-Pierre Cabaniols, Fayza Daboussi, Sylvain Arnould, Christophe Perez, Philippe Duchateau, Frederic Paques, Francisco J. Blanco & Guillermo Montoya

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Methods Mol Biol. 2008;435:31-45.

Robust cell line development using meganucleases.
Cabaniols JP, Pâques F.

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Mol Ther. 2008 Aug;16(8):1490-9. Epub 2008 Jun 17.

Stable and functional lymphoid reconstitution in artemis-deficient mice following lentiviral artemis gene transfer into hematopoietic stem cells.
Benjelloun F, Garrigue A, Demerens-de Chappedelaine C, Soulas-Sprauel P, Malassis-Séris M, Stockholm D, Hauer J, Blondeau J, Rivière J, Lim A, Le Lorc'h M, Romana S, Brousse N, Pâques F, Galy A, Charneau P, Fischer A, de Villartay JP, Cavazzana-Calvo M.

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Nucleic Acids Res. 2008 Apr;36(7):2163-73. Epub 2008 Feb 14.

Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences.
Fajardo-Sanchez E, Stricher F, Pâques F, Isalan M, Serrano L.

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J Biol Chem. 2008 Feb 15;283(7):4364-74.

Generation and analysis of mesophilic variants of the thermostable archaeal I-DmoI homing endonuclease.
Prieto J, Epinat JC, Redondo P, Ramos E, Padró D, Cédrone F, Montoya G, Pâques F, Blanco FJ.

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Curr Gene Ther. 2007 Feb;7(1):49-66.

Meganucleases and DNA double-strand break-induced recombination: perspectives for gene therapy.
Pâques F, Duchateau P.

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Nucleic Acids Res. published online on April 22, 2007 DOI: 10.1093/nar/gkm183

The C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavage.
Jesus Prieto, Pilar Redondo, Daniel Padro, Sylvain Arnould, Jean-Charles Epinat, Frederic Paques, Francisco J. Blanco1 and Guillermo Montoya

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Journal of molecular biology 2007;371(1):49-65.

Engineered I-CreI derivatives cleaving sequences from the human XPC gene can induce highly efficient gene correction in mammalian cells.
Arnould Sylvain; Perez Christophe; Cabaniols Jean-Pierre; Smith Julianne; Gouble Agnès; Grizot Sylvestre; Epinat Jean-Charles; Duclert Aymeric; Duchateau Philippe; Pâques Frédéric

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Nucleic Acids Res. 2006;34(22):e149 DOI: 10.1093/nar/gkl720

A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences.
Smith J, Grizot S, Arnould S, Duclert A, Epinat JC, Chames P, Prieto J, Redondo P, Blanco FJ, Bravo J, Montoya G, Pâques F, Duchateau P.

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J Gene Med 2006; 8: 616-622. DOI: 10.1002/jgm.879

Efficient in toto targeted recombination in mouse liver by meganuclease-induced double-strand break.
Agnès Gouble, Julianne Smith, Sylvia Bruneau, Christophe Perez, Valérie Guyot, Jean-Pierre Cabaniols, Sophie Leduc, Laurence Fiette, Patrick Avé, Béatrice Micheau, Philippe Duchateau, Frédéric Pâques

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Nucleic Acids Res. 2005 33(20):e178

In vivo selection of engineered homing endonucleases using double-strand break induced homologous recombination.
Patrick Chames, Jean-Charles Epinat, Sophie Guillier, Amélie Patin, Emmanuel Lacroix and Frédéric Pâques

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J Mol Biol. 2006 Jan 20;355(3):443-58. Epub 2005 Nov 15.

Engineering of Large Numbers of Highly Specific Homing Endonucleases that Induce Recombination on Novel DNA Targets.
Sylvain Arnould, Patrick Chames, Christophe Perez, Emmanuel Lacroix, Aymeric Duclert, Jean-Charles Epinat, François Stricher, Anne-Sophie Petit, Amélie Patin, Sophie Guillier, Sandra Rolland, Jesús Prieto, Francisco J. Blanco, Jerónimo Bravo, Guillermo Montoya, Luis Serrano, Philippe Duchateau and Frédéric Pâques.

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BioTechniques® July 2005 ; Volume 39, Number 1: pp 109-115

Factors affecting double-strand break-induced homologous recombination in mammalian cells.
Christophe Perez, Valérie Guyot, Jean-Pierre Cabaniols, Agnès Gouble, Beatrice Micheaux, Julie Smith, Sophie Leduc, Frédéric Pâques, and Philippe Duchateau

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Nucleic Acids Res. 2003 Jun 1;31(11):2952-62

A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells.
Epinat JC, Arnould S, Chames P, Rochaix P, Desfontaines D, Puzin C, Patin A, Zanghellini A, Paques F, Lacroix E.

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Mech Dev. 2002 Oct;118(1-2):91-8

I-SceI meganuclease mediates highly efficient transgenesis in fish.
Thermes V, Grabher C, Ristoratore F, Bourrat F, Choulika A, Wittbrodt J, Joly JS.

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